Endocrinology and Metabolic Diseases
Endocrinology and Metabolic Diseases
Asst. Prof. İsmail ENGİN
Education Information
Uludağ University Faculty of Medicine 2005–2012
University of Health Sciences, Haseki Training and Research Hospital 2013–2017
University of Health Sciences, Sultan Abdülhamid Han Training and Research Hospital 2020–2023
Turkish Society of Endocrinology and Metabolism (TEMD)
- Second Place Award for Oral Presentation
Istanbul Medeniyet University 4th Endocrinology Days, Istanbul, December 2025 - Third Place Award for Poster Presentation
45th Turkish Congress of Endocrinology and Metabolic Diseases, Antalya, April 2024
Articles Published in International Peer-Reviewed Journals
Ayçiçek B, Tuna MM, Engin İ, et al. Temporal Variation of Biochemical Markers and Adenoma Predictors in Normocalcemic Primary Hyperparathyroidism: A Multicenter Retrospective Analysis. Clinical Endocrinology, 2025. doi:10.1111/cen.70024
Hoca E, Cangir B, Ahbab S, Şahin Sİ, Çiftçi Öztürk E, Urvasızoğlu AÖ, Kalaycı N, Engin İ, Ataoğlu HE. The Triglyceride/HDL Ratio as a Non-Invasive Marker for Early-Stage NAFLD: A Retrospective Cross-Sectional Study of 2588 Patients. Diagnostics. 2025;15(16):2045. doi:10.3390/diagnostics15162045
Engin İ, Tuna MM, Köroğlu EY, et al. Clinical characteristics, mid-term outcomes and management of asymptomatic primary hyperparathyroidism: A multicentre retrospective cohort study. Endocrine. 2025. doi:10.1007/s12020-025-04380-y
Topsakal Ş, Yaylalı GF, Yarar Z, et al. Multicenter Study on the Clinical Characteristics, Diagnosis, and Treatment Outcomes of Insulinoma. Clinical Endocrinology. 2025;103(1):57-65. doi:10.1111/cen.15255
Hoca E, Kalaycı N, Ahbab S, Engin İ, Ataoğlu HE. The Impact of Metformin on BNP Levels: A Potential Cardioprotective Role in Type 2 Diabetes. Journal of Clinical Medicine. 2025;14(8):2733. doi:10.3390/jcm14082733
Şenoymak MC, Erbatur NH, Engin İ, Yönem A. The Impact of Patient Anxiety and Pain Perception on the Adequacy of Thyroid Fine-Needle Aspiration Biopsy Samples: A Prospective Study. Acta Endocrinologica. 2024;20(1):39-44. doi:10.4183/aeb.2024.39
Şenoymak MC, Engin İ, Erbatur NH, Canbek S, Deniz F, Yönem A. A rare disorder of sex development; de la chapelle syndrome. DAHUDER Medical Journal. 2023;3(2):72-75.
Engin İ, Duman AE, Ataoğlu HE, Örmeci AÇ, Poturoğlu Ş. Predictors of Eligibility for Reimbursement of Antiviral Treatment in HBe-Ag Negative Chronic Hepatitis B Patients With High ALT Levels. Journal of Surgery and Medicine. 2022;6:705-708.
Engin İ. Adult Growth Hormone Deficiency and Replacement Therapy: Current Approaches. Archives of Clinical Hypertension. 2025;11(1):005-008. doi:10.17352/ach.000037
Engin İ, Tuna MM. Adrenalectomy Improves Muscle Strength in Patients with Mild Autonomous Cortisol Secretion: A Comparative Study. Medicina. 2026;62(3):553. doi:10.3390/medicina62030553
Tuna MM, Ayçiçek B, Engin İ, et al. The Fate of Normocalcemic Hyperparathyroidism: Insights from a 3-Year Multicenter Follow-Up. Hormone and Metabolic Research. 2026. doi:10.1055/a-2812-1864
Ayçiçek B, Tuna MM, Engin İ, et al. Longitudinal Analysis of Biochemical, Imaging, and Adenoma Size Changes in Primary Hyperparathyroidism. Experimental and Clinical Endocrinology & Diabetes. 2026;134(2):53-62. doi:10.1055/a-2804-1682
Engin İsmail, Tuna Mazhar Müslüm. Psychological Burden in Mild Autonomous Cortisol Secretion: A Cross-Sectional Comparative Study. Medical Principles and Practice. 2026. doi:10.1159/000552080
Presentations at International Scientific Meetings
Şenoymak MC, Erbatur NH, Engin İ, Yönem A. Is Patient Anxiety A Risk Factor for FNAB Sample Adequacy? Poster Presentation, 25th European Congress of Endocrinology, Istanbul, May 13–16, 2023.
Hoca E, Engin İ. The Relationship Between Metformin and Vitamin B12 Levels in Patients Admitted to a Diabetes Outpatient Clinic. Oral Presentation, EURASIA 3rd International Scientific Research and Innovation Congress, Ankara, January 29–31, 2024.
Pişkin Ural H, Tuna MM, Engin İ. Contribution of ACR TI-RADS Scoring System to Surgical Decision-Making in Bethesda Category III Thyroid Nodules. Oral Presentation, 24th European Congress of Internal Medicine, Vienna, March 25–28, 2026.
International Books or Book Chapters
Engin İsmail. “Treatment of Type 2 Diabetes Mellitus”, Endocrinology Quick Notes. Editor: Prof. Dr. Özlem Turhan İyidir. Istanbul, 1st Edition, 2025, pp. 439–443.
Engin İsmail, Yönem Arif. “Hypoparathyroidism”, University of Health Sciences Hamidiye Faculty of Medicine Student Lecture Notes: Internal Medicine. Editor: Prof. Dr. Erdoğan Çetinkaya. Istanbul, 1st Edition, 2024, pp. 198–200.
Engin İsmail, Tuna Mazhar Müslüm. “Diabetes Management in Patients with Malignancy”, Diabetes Management in Special Patient Groups. Editor: Prof. Dr. Hayriye Esra Ataoğlu. Ankara, 1st Edition, 2024.
Articles Published in National Peer-Reviewed Journals
Karahan E, Engin İ, Yönem A. The Effects of the COVID-19 Pandemic Process on the Treatment and Follow-up of Diabetes Mellitus in Type 2 Diabetic Patients. Hamidiye Medical Journal. 2024;5(1):13-20. doi:10.4274/hamidiyemedj.galenos.2024.63835
Engin İ. Impact of Hyperprolactinemia on Hemoglobin and Neutrophil-to-Lymphocyte Ratio: A Cross-Sectional Study in Patients with Prolactinoma. Hippocrates Medical Journal. 2025;5(2):68-75. doi:10.58961/hmj.1748826
Presentations at National Scientific Meetings
Engin İ, Tuna MM. Determination of Malignancy Rates in Bethesda Category 3 and 4 Thyroid Nodules. Istanbul Medeniyet University 4th Endocrinology Days, Istanbul, December 12–13, 2025. Second Place Award for Oral Presentation.
Akbal A, Engin İ, Ekşioğlu M, Aras N, Tuna MM. Determining the Malignancy Potential of Thyroid Nodules from Ultrasound Images Using Deep Learning. 46th Turkish Congress of Endocrinology and Metabolic Diseases, Antalya, April 30–May 4, 2025.
Karahan E, Engin İ, Yönem A. The Effects of the COVID-19 Pandemic Process on the Treatment and Follow-up of Diabetes Mellitus in Patients with Type 2 Diabetes. 25th National Internal Medicine Congress, Antalya, November 8–12, 2023.
Dinçer C, Kaplan M, Engin İ, Çakır S. The Relationship Between Dyspepsia and C-Peptide at Diagnosis in Newly Diagnosed Type 2 Diabetes Patients Started on Metformin Treatment. 24th National Internal Medicine Congress, Antalya, October 19–23, 2022.
Özsarı L, Atış Ö, Çakır Güney B, Engin İ. A Rare Cause of Hypoglycemia: Malignant Insulinoma. 5th Internal Medicine Congress, Antalya, June 2–5, 2022.
Engin İ, Hoca E. The Effects of Thyroid Antibody Levels on Glycemic Regulation in Patients with Type 2 Diabetes Mellitus. Istanbul Medeniyet University Endocrinology Days, Istanbul, December 2–3, 2022.
Engin İ, Şenoymak MC, Deniz F, Yönem A. A Rare Disorder of Sex Development Presenting with Gynecomastia: 46 XX Testicular Disorder. Istanbul Medeniyet University Endocrinology Days, Istanbul, December 2–3, 2022.
Other Publications
Topsakal Ş, Yaylalı GF, Yarar Z, et al. Clinical presentation, diagnosis, treatment and prognosis in patients with insulinoma: a multicenter study. 45th Turkish Congress of Endocrinology and Metabolic Diseases, Antalya, April 17–21, 2024. Third Place Award for Poster Presentation.
Yavuz S, Kılıç Ş, Asal S, Erdem A, Engin İ, Orhan AL. Massive Pericardial Effusion Associated with Hypothyroidism. 44th Turkish Congress of Endocrinology and Metabolic Diseases, Istanbul, May 12–13, 2023.
Erkoç RB, Şenoymak MC, Erbatur NH, Engin İ, Deniz F, Yönem A. A Rare Case of Hypoglycemia with Secondary Adrenal Insufficiency and Insulinoma. 25th National Internal Medicine Congress, Antalya, November 8–12, 2023.
Seçgin Demir E, Engin İ, Kaplan M. Evaluation of Metabolic Syndrome Risk by TG/HDL Measurement in Individuals with Hyperprolactinemia and Normal Body Mass Index. 25th National Internal Medicine Congress, Antalya, November 8–12, 2023.
Engin İ, Özsarı L, Yönem A. How Far Should We Search for a Parathyroid Adenoma? Endokurs 5th Postgraduate Training Course, Antalya, November 10–14, 2021.
Engin İ. A Difficult Case of Acromegaly. 43rd Turkish Congress of Endocrinology and Metabolic Diseases, Antalya, May 18–22, 2022.
Engin İ, Hoca E, Ahbab S, Ataoğlu HE. Goodpasture Syndrome. 8th National Haseki Medicine Congress, Antalya, May 4–7, 2017.
Engin İ, Hoca E, Ataoğlu HE. A Case Report of Hemolytic Uremic Syndrome. 18th National Internal Medicine Congress, Antalya, October 12–16, 2016.
Engin İ, Yamak M, Hoca E, Seçmeler Ş, Ataoğlu HE. Amiodarone-Induced Thyrotoxicosis. 6th Istanbul Internal Medicine Clinics Meeting, Istanbul, November 18–20, 2016.
Projects
Investigation of the Regulation Status of Glycemic and Other Metabolic Parameters in Adult Patients with Diabetes in Türkiye-2
TEMD-2 Study
A multicenter cross-sectional study supported by the Turkish Society of Endocrinology and Metabolism.
Project Approval No: 2022/P02 — 03.07.2022
ClinicalTrials.gov: NCT06347445
Start Date: 06.04.2022
End Date: 01.12.2025
Role: Sub-Investigator
LEADER: Liraglutide Effect and Action in Diabetes — Evaluation of Cardiovascular Outcome Results
An international, multicenter, randomized, double-blind, placebo-controlled clinical trial.
Project Code: EX2211-3748
Start Date: 2014
End Date: 2016
Role: Sub-Investigator